North Carolina District 2 coordinates several interleague arrangements for member leagues. The purpose of the interleague schedule is to provide a structure for several leagues with fewer than four teams in a division.
Information for the Interleague configurations will be listed below. Game Changer will be utilized for scoring and pitch count records.
| Division Standings | Interleague Rules |
| Machine Pitch Baseball | Link |
| Minors Baseball | Link |
| Majors Baseball | Link |
| Intermediate Baseball | Link |
| Junior Baseball | Link |
| Senior Baseball | Link |
| Coach Pitch Softball | Link |
| Minors Softball | Link |
| Majors Softball | Link
|
| Senior Softball | Link |